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Symbol
Name
ID
Picalm
phosphatidylinositol binding clathrin assembly protein
MGI:2385902
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Acute myeloid leukemia
Disease(s) Associated with PICALM
acute myeloid leukemia

Mouse Phenotypes
enlarged spleen
abnormal B cell differentiation
decreased CD4-positive, alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
decreased spleen B cell follicle number
Availability Mouse Genotype
Picalmtm1Towa/Picalmtm1Towa
Picalmtm1.1Tmae/Picalmtm1.1Tmae
Tg(Mx1-cre)1Cgn/0  (conditional)
Picalmtm1.1Tmae/Picalmtm1.1Tmae
Commd10Tg(Vav1-icre)A2Kio/Commd10+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory